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01 Record

CVE-2025-68463

Bio.Entrez in Biopython through 186 allows doctype XXE.

MediumPUBLISHEDCNA: mitre
CNA base score4.9 CVSS v3.xCVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:C/C:L/I:N/A:L

02 Description

Bio.Entrez in Biopython through 186 allows doctype XXE.

03 Exploitation and scoring

Exploitation
Assessed, none found. CISA's assessment recorded neither public exploit code nor evidence of exploitation when it was made.
SSVC decision
  • ExploitationnoneCISA recorded no public exploit code and no evidence of exploitation.
  • AutomatablenoAt least one step from reconnaissance to exploitation cannot be reliably automated.
  • Technical ImpactpartialSuccessful exploitation gives limited control of the vulnerable component.
CISA publishes the decision points, not a final SSVC decision. The decision also depends on mission and well-being impact, which is a property of your deployment rather than of the vulnerability.
EPSS probability
0.31% probability of exploitation activity in the next 30 days.
EPSS percentile
Equal to or higher than the score of 24.2% of scored records. A rank, not a probability.
NVD base score
4.9 (CVSS v3.x), scored by the NVD independently of the CNA.
NVD CVSS vector
CVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:C/C:L/I:N/A:L
NVD analysis status
Deferred. NVD last modified this record on 2026-10-13.
Red Hat severity
Moderate. Red Hat's rating for its own products, not a CVSS rating.

Exploit-prediction scores from FIRST. Independent scoring and analysis status from the NVD. Vendor severity from Red Hat. Exploitation assessment and catalog membership from CISA.

04 Metadata

Published
2025-12-18 05:40Z10 MO AGO
Last updated
2026-05-08 18:28Z5 MO AGO
Reserved
2025-12-18
Assigning CNA
mitre
Record state
PUBLISHED
Severity
Medium (CVSS 4.9)
CNA CVSS vector
CVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:C/C:L/I:N/A:L
Weaknesses
  • CWE-611Improper Restriction of XML External Entity ReferenceBase
Data version
5.2
Document digest
1306b09085d9b374056e3d083d1ca1735a1879d24592ab4f25bf1713774ceed8

05 Affected products

VendorProductVersionsPlatforms
BiopythonBiopython0 to 186—

06 References

07 Fixed in

Debian 12

  • python-biopython
    No fix yet

Source: Debian Security Tracker, the Debian security team. Received through OSV.dev. Reformatted by exploit.cc.

Debian 13

  • python-biopython
    No fix yet

Source: Debian Security Tracker, the Debian security team. Received through OSV.dev. Reformatted by exploit.cc.

Debian 14

  • python-biopython
    Fixed in 1.87+dfsg-1

Source: Debian Security Tracker, the Debian security team. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 16.04 LTS

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 18.04 LTS

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 20.04 LTS

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 22.04 LTS

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 24.04 LTS

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 25.10

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 26.04 LTS

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

Ubuntu 26.10

  • python-biopython
    No fix yet

Source: Ubuntu, Canonical Ltd. Licensed under CC BY-SA 4.0. Received through OSV.dev. Reformatted by exploit.cc.

A release or ecosystem missing from this list has no record here. It may be unaffected or not covered by the source. Source notices and licences.